Botox vs. Dermal Fillers: Which Facial Aesthetics Treatment Should You Do?

You glance in the mirror and notice lines around your eyes when you smile, or maybe deeper folds forming around your mouth even when your face is at rest. Whether it’s crow’s feet from years of laughter or a loss of volume that’s leaving your cheeks looking less lifted, you might be looking for ways to maintain a refreshed appearance. If you’ve done even a little research, you’ve likely come across two of the most popular injectables: Botox and fillers.

At Serotonin Centers, we specialize in helping you feel and look your best with facial aesthetic treatments. In this article, we’ll guide you through the key differences between Botox and dermal fillers and which option might suit your goals best.

Mechanism of action

Botox

Botox is a neuromodulator that works by temporarily blocking nerve signals to targeted muscles. By limiting muscle movement, Botox reduces the appearance of dynamic wrinkles caused by repetitive facial expressions like frowning, squinting, or raising your eyebrows. The result is smoother skin in areas that are prone to creasing from movement, such as the forehead.

Dermal fillers

Dermal fillers are gel-like substances, most commonly made from hyaluronic acid, that are injected beneath the skin to restore lost volume, smooth out static wrinkles, or enhance facial contours. Instead of affecting muscle movement, fillers work by physically “filling in” areas that have become hollow or creased, like the nasolabial folds, lips, or under-eye hollows.

Treatment areas

Botox

Botox is ideal for treating dynamic wrinkles primarily in the upper third of the face. It’s most commonly used on:

• Forehead lines
• Frown lines (between the brows)
• Crow’s feet (around the eyes)

Dermal fillers

Fillers shine when used to restore volume or smooth deeper, static wrinkles that are visible even when your face is relaxed. Common treatment areas include:

• Nasolabial folds
• Cheeks
• Lips
• Under-eye hollows
• Marionette lines
• Jawline and chin

Duration of results

Botox

The effects of Botox typically last 3 to 4 months. After that, muscle activity gradually returns, and dynamic facial wrinkles may begin to reappear. Maintenance treatments are recommended several times a year to sustain your results.

Dermal fillers

Fillers tend to have longer-lasting effects, typically 6 to 18 months, depending on the type of filler and the treatment area. Some formulations meant for deeper injection or structural support can even last up to 24 months.

Onset of results

Botox

Botox doesn’t work instantly. It typically takes 3 to 7 days for the initial effects to become visible, with the full results typically settling in around the two-week mark. It’s essential to plan accordingly if you’re preparing for a significant event.

Dermal fillers

Fillers offer immediate gratification. You’ll notice plumper, smoother skin right after your appointment, although mild swelling or bruising may temporarily affect the appearance. Once any post-treatment effects subside, your results are fully visible.

Side effects and safety

Botox

Botox is widely considered safe when administered by trained professionals. Side effects are rare but may include localized bruising, redness, or mild swelling at the injection site. Less common risks include eyelid drooping or asymmetry, which are typically temporary.

Dermal fillers

Fillers are also safe, especially those based on hyaluronic acid, which can be dissolved if needed. Mild side effects, such as redness, swelling, and tenderness, are common and typically resolve within a few days. In rare cases, small lumps can also occur.

Which facial aesthetics treatment should you do?

Deciding between Botox and fillers depends on your aesthetic enhancement goals, the type of wrinkles you’re targeting, and how long you want the results to last. Here’s a quick guide to help you decide.

You should choose Botox if:

• You want to reduce expression lines or prevent them from forming
• You are mostly concerned with forehead lines or crow’s feet
• You prefer a subtle, natural softening of movement-based wrinkles
• You are exploring preventative treatments in your 20s or 30s

You should choose dermal fillers if:

• You want to restore volume in cheeks, lips, or under-eyes
• You have static wrinkles that show even when your face is at rest
• You are looking to contour or reshape facial features
• You want results that are visible immediately and last longer

Or better yet, why choose at all?

Botox and dermal fillers don’t have to be mutually exclusive. In fact, they’re often used together for a more comprehensive facial rejuvenation strategy. This combined approach is known as a "liquid facelift," and it provides enhanced results without the need for surgery. Botox smooths the upper face while fillers restore volume and balance in the mid and lower face.

At Serotonin Centers, we take an individualized approach to aesthetic care, helping you decide if one or both of these treatments will give you the youthful, refreshed look you’re after. Whether you want to soften wrinkles, enhance facial volume, or simply feel more confident in your skin, Serotonin Centers offers a personalized aesthetic experience rooted in science. Book your consultation today and take the next step toward looking as vibrant as you feel.