Lip Filler Prep: What to Know Before Your First Visit

Preparing for lip filler is just as important as the treatment itself. When you understand what to do ahead of time, including how to care for your skin, what to avoid, and what to expect, you set yourself up for smoother healing and more natural, balanced results. Lip fillers may be minimally invasive, but the planning that happens beforehand plays a big role in how confident you feel walking out of your appointment.

At Serotonin Centers, your treatment begins long before the syringe. Our providers emphasize thoughtful, personalized preparation that supports your goals, reduces unnecessary swelling, and helps ensure your results look refined and harmonious. Below, you’ll learn the essential steps to follow before your first lip filler visit.

Lip filler preparation guidelines for optimal results

Avoid blood-thinning medications and supplements

To reduce the risk of bruising and swelling, avoid over-the-counter blood thinners like ibuprofen, aspirin, and naproxen for at least 5 to 7 days before your appointment, unless a physician has directed otherwise. Certain supplements, including fish oil, vitamin E, ginkgo biloba, garlic, and St. John’s wort, can also increase bleeding risk and should be paused. If you’re unsure whether something on your list is a blood thinner, check with your provider before making changes.

Limit alcohol and caffeine before your visit

Alcohol and caffeine can dilate blood vessels, which increases your likelihood of post-treatment bruising and swelling. Try to avoid alcohol entirely for 24 to 48 hours before your appointment, and limit caffeine the morning of. Hydration works in your favor, so drink plenty of water instead.

Stay away from harsh skincare treatments

Peels, retinoids, aggressive exfoliation, and facial waxing near the lips can make the skin more sensitive. Avoid these for at least one week prior to your appointment. A calmer skin barrier ensures a smoother experience and minimizes unnecessary irritation or redness afterward.

Plan your visit around major events

Lip filler often comes with temporary swelling, sometimes subtle, sometimes more noticeable, depending on your body’s response. If you have a wedding, photoshoot, speaking engagement, or important trip coming up, schedule your appointment at least 7 to 10 days beforehand. This window ensures time for swelling to subside and for your results to settle naturally.

Prevent cold sore flare-ups if you’re prone

If you carry the herpes simplex virus and are prone to cold sores, injections around the mouth can trigger an outbreak. Let your provider know in advance. You may be advised to start a preventative antiviral medication before the visit to reduce the risk of a flare-up.

Arrive with a clean, product-free face

Makeup, lip gloss, balm, or foundation should be removed before treatment, especially around the mouth. Arriving with a fresh, clean face makes the process easier, helps maintain sterility, and minimizes the chance of irritation.

What to know before your lip filler appointment

The type of filler being used

Most lip fillers are made of hyaluronic acid (HA), a naturally occurring substance that attracts hydration and provides softness and subtle volume. Your injector will choose a formula based on your goals, whether that’s a slight enhancement, definition along the Cupid’s bow, or more noticeable fullness. Knowing which filler will be used can help you stay informed.

What “natural results” really look like

Photos online can create unrealistic expectations. A skilled injector focuses on harmony by enhancing shape, projection, and balance rather than overfilling. You can expect your lips to look slightly larger after treatment due to swelling, but they will soften and refine over the next few days. Discuss your goals openly so your provider can tailor the result to your features.

Sensation and comfort during treatment

Most clients describe injections as mildly uncomfortable rather than painful. Topical numbing cream is typically applied for 10 to 15 minutes, and many HA fillers contain lidocaine to increase comfort. Knowing this in advance can ease any anxiety and help you relax during the process.

How long your results will last

Lip filler longevity depends on the type of filler used, your metabolism, and your lifestyle. Most HA fillers last 6 to 12 months. If this is your first treatment, expect the filler to fade a bit faster. Your provider will guide you on maintenance schedules to keep your shape consistent.

Possible side effects and what’s considered normal

Temporary swelling, tenderness, and mild bruising are common in the first few days. Small lumps or unevenness may appear as swelling shifts but often resolve as the filler integrates. Severe pain, skin blanching, or unusual discoloration are not typical: your provider will review warning signs so you know when to call.

Aftercare steps you’ll need to follow

Avoid strenuous exercise, heat exposure, drinking through a straw, or applying pressure to the lips for the first 24 hours. Ice can help minimize swelling, and sleeping with your head elevated is beneficial. Understanding aftercare in advance helps you plan for a smooth recovery.

The value of a consultation before committing

Your first visit is rarely a “walk-in and inject” experience. At Serotonin Centers, your injector assesses your facial proportions, reviews your medical history, discusses your goals, and creates a plan that aligns with your anatomy to ensure safe and flattering results.

Preparing for lip filler is an essential part of achieving a beautiful, natural outcome, and when you know exactly what to expect, the experience becomes far more comfortable. At Serotonin Centers, we are committed to guiding you through each step of the process so your results align with your goals and feel authentically you. Schedule your consultation today.